Apak-212

: Research into KRAB-zinc finger proteins has shown that proteins like ZNF498 and APAK can promote carcinogenesis by suppressing p53-induced increases in pro-apoptotic genes like Puma and Bax .

Solid‑phase peptide synthesis (SPPS) using Fmoc chemistry on a Rink amide resin. Side‑chain protection groups: Arg(Pbf), Lys(Mtt), Trp(Boc). Peptide cleaved, precipitated, and purified by RP‑HPLC (C18, 5‑95 % ACN, 0.1 % TFA). Purity > 98 % confirmed by MALDI‑TOF MS (calculated m/z 2542.3 Da). APAK-212