Are you getting a (like a black screen) when you try to use them?
If you have tried to use Action Replay or cheat devices on this specific title, you have likely encountered frustration. The game is notoriously finicky. But the short answer is , but only if you understand the specific hardware limitations, memory addresses, and code types required for this particular port.
You're looking for working Gecko codes for Need for Speed: Most Wanted on the GameCube. Here are some features and codes that might interest you: